There are about 40 diseases researched with fluoride side effects. (Click on the study links to get more details) Some of them are
Childhood Cognitive Disorders
Low/Impaired Intelligence Quotient (IQ)
Prenatal Nutrition: negative impact on Learning/Intelligence of Offspring
Infertility in male and female
Impaired children growth
Pineal gland diseases
Low sperm quality
Breast feeding concerns
Brain: Microglial Activation
Hair Loss and quaility problems
Neurodegenerative disease Study 1. Fluoride is neurotoxic, diseases : Childhood Cognitive Disorders, Cognitive Decline/Dysfunction, Fluoride Toxicity , Fluorosis, Intelligence Quotient (IQ): Low/Impaired, Prenatal Nutrition: Learning/Intelligence of Offspring
Exposure to high levels of fluoride may adversely influence children’s intelligence development.
Study 2. Infant formula consumption may be associated with an increased risk of developing at least some detectable level of enamel fluorosis.
Study 3. The problem substance fluoride leads to Ectopic Calcification, Fluoride Toxicity , Pineal Gland Calcification , Pineal Gland Diseases
Fluoride deposits in the pineal gland with age and is associated with enhanced gland calcification.
Study 4. Infants fully formula-fed on formulae prepared with optimally fluoridated water (0.7-1.0 mg/L) have a high probability of exceeding the upper limit for fluoride and are at increased risk of dental fluorosis
Study 5. The results suggest that overexposure to fluoride (160-320 μM) can induce cytotoxicity and regulate relevant genes expression.
Study 6. Fluoride is associated with diseases- Brain Inflammation , Fluoride Toxicity ,Neurodegenerative Diseases, Oxidative Stress
Aluminium, fluoride and a combination of aluminium-fluoride treatments caused an increase in brain lipid peroxidation products and reactive oxygen species formation.
Study 7. Fluoride is cardiotoxic and responsible for Arterial Calcification, Atheroma, Atherosclerosis, Chronic Kidney Disease (CKD), Ectopic Calcification, Fluoride Toxicity
Effect of water fluoridation on the development of medial vascular calcification in uremic rats.
Study 8. Fluoride could pose a great threat to thyroid endocrine system.
Study 9. Fluoride exposure over several generations results in adverse histopathological and biochemical changes in lung tissue.
Study 10. Fluoride is neurotoxic , responsible for diseases Fluoride Toxicity , Hypothyroidism, Prenatal Chemical Exposures, Prenatal Nutrition: Learning/Intelligence of Offspring
High fluoride exposure has multigenerational and cumulative adverse effects on thyroid status, brain health and learning memory in rats.
Study 11. Prolonged ingestion of fluoride through drinking water, particularly with high doses, induced significant histopathological and biochemical changes leading to myocardial tissue damage.
Study 12. Sodium fluoride is genotoxic and teratogenic; leads to Fluoride Toxicity , Huntington Disease, Obsessive-Compulsive Disorder, Prenatal Chemical Exposures, Schizophrenia,Tourette Syndrome
Sodium flouride exposure during pregnancy may interfere with normal development and increase the risk of neurological and psychiatric disorders in adulthood.
Study 13. Fluoride and sofium fluoride has anti-infertility action, results into Fluoride Toxicity , Infertility: Male, Sperm Quality: Low
Sodium fluoride administrated in drinking water of 2, 4, and 6 ppm concentration for 6 months to male rats adversely affected their fertility and reproductive system.
Study 14. Sodium fluoride exposure changed histological structure and ultrastructure of hypothalamus–pituitary–testicular axis and significantly increased the malformation ratio of sperm.
Study 15. Sodium fluoride may adversely affect early embryonic development by disrupting the methylation of H19 and Peg3 through downregulation of DNMT1.
Study 16. Fluoride is associated with hypothyroidism
Due to the ability of fluoride to inhibit the production of thyroid hormones, a transition to low exposure may result in hyperthyroidism associated psychosis.
Study 17. Fluoride and sodium fluoride are the risk factor for many Chronic Kidney Disease (CKD), Fluoride Toxicity , Kidney Damage
Excess fluoride in drinking water and in the locally grown food in the affected areas might lead to chronic kidney diseases.
Study 18. Fluoride and sodium fluroide damages teeth
Excessive amounts of fluoride cause autophagy of HAT-7 cells, indicating that autophagy is involved in dental fluorosis.
Study 19. A has shown that the toxicity of fluoride is determined by environmental conditions and the positive cations present. At a pH typical of gastric juice, fluoride is largely protonated as hydrofluoric acid HF. Industrial fluoride ingested from treated water enters saliva at levels too low to affect dental caries. Blood levels during lifelong consumption can study harm heart, bone, brain, and even developing teeth enamel. The widespread policy known as water fluoridation is discussed in light of these findings.
Exposure to high fluoride concentrations in drinking water is associated with decreased birth rates.
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